I noticed the PTT Hotkey didn't work as it should because my transmissions were interrupted by others. I looked in the settings after the flight and found the checkbox for that hotkey wasn't ticked (PTT time is not set to 0). I reticked it and this was saved after a restart of PF3.
But the same problem on my next flight. And after the flight the checkbox again was unticked.
Please let me know if you cannot reproduce this issue and need my logs.
Regards
Ralf