OK, now I did not change the com radio frequency, However, I did consider if that was the problem, and I tried to run the PF3_Display tool, something I have not run in, I don't know how long, to check on the en route frequencies. But it would not run. I got the error that to run PF3_Display you needed to run MSFS and PF3 had to be connected to MSFS before I could run PF3_Display, which made me think there was something serious that had gone wrong.
I guess my follow up question is if there is a way I can check what the frequency should be during flight so if this happens again I will be able to continue
Thanks