After failing the update (I'm guessing a stray .dll wasn't unloaded somewhere) I uninstalled and reinstalled.
I re-ran MakeRunways (mentioned nowhere in the documentation) and rebuilt the database (also not mentioned for installation)
I attempt to open a flight plan, and get a message about selecting the proper folder for what sim I'm using, but then after closing that, the program crashes and I'm unable to open any folder.
Included are the logs.