Frank,
you could try the PSS A319-A321 profile,as that is the only one done for that type of a/c.
If it does not work,then i could make one just for the Wilco range if you are prepared to help in testing.
As for the PMDG 747,that's strange because i used it only last sunday for a flight and everything was just fine.
Is there anything on your system that could be interfering with FDC,say spyware or AV,anything else that was added recently,could you take some screenshots if at all possible of the ctd,what is your BlackBox reading in FDC,